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masteron side effects

Mucolytic agent. It has sekretomotornym, sekretoliticheskim and expectorant action; stimulates serous cells of glands of bronchial mucosa, increases the amount of mucous secretion and release of a surface-active substance (surfactant) in the alveoli and bronchi; normalizes impaired ratio of serous and mucous components of phlegm. By activating the hydrolyzing enzymes and increasing the release of lysosomes of Clara cells, reduces the viscosity of sputum. It increases motor activity of ciliated epithelium, increases mucociliary transport.

Once inside the action occurs within 30 minutes.

Pharmacokinetics

Absorption – high (if any routes of administration), time to maximum concentration (TC max ) – h 2, connection with plasma proteins – 80%. It penetrates through the blood-brain barrier, placental barrier, excreted in breast milk.

It is metabolized in the liver by conjugation forming pharmacologically inactive metabolites: dibromantranilovuyu and glucuronic acid conjugates. The half-life (T 1/2 ) – 7-12 hours and total T 1/2 . 22h reaches excreted by the kidneys in plasma (masteron side effects and its metabolites): 90% in the form of water-soluble metabolites in unmodified form – 5%.

The half-life of masteron side effects and its metabolites increased with severe chronic renal failure; It does not change in the human liver.

Indications for use:

 

Diseases of the respiratory tract to form a viscous mucus:

· Acute and chronic bronchitis;

· Pneumonia;

· Chronic obstructive pulmonary disease;

· Asthma with obstruction of sputum discharge;

· Bronchiectasis.

 

Contraindications:

 

· – Hypersensitivity to masteron side effects or to any other component of the drug;

· – Pregnancy (I term);

· – Peptic ulcer and 12 duodenal ulcer in the acute stage;

· – Epileptic syndrome;

· – A violation of the bronchi motor, large amounts of allocated secret (the danger of stagnation secretion in the bronchi);

· – The age of 12 years.

C care

Liver failure, renal failure, peptic ulcer and 12 duodenal ulcer (in history), pregnancy (II-III trimester), lactation, as well as patients with impaired cough reflex or impaired mucociliary transport due to the possibility of accumulation of phlegm; Patients with asthma (masteron side effects may exacerbate cough).

Pregnancy and lactation:

The drug should not be used in I trimester of pregnancy. Use of the drug during the period of breastfeeding is only possible if the expected effect of therapy outweighs the potential risk to the fetus and infant (up to now there is no reliable data on the negative impact of the drug on the fetus and infants).

Dosage and administration:

Inside, during a meal, with a small amount of liquid. Adults and children over 12 years: 1 capsule 75 mg in the morning.

Not recommended for use without a doctor’s prescription in more than 4-5 days.

Side effect:

Allergic reactions: skin rash, urticaria, angioedema, in some cases – allergic contact dermatitis, anaphylactic shock.

Rarely – weakness, headache, diarrhea, dry mouth and respiratory tract, rash, runny nose, constipation, dysuria.

With prolonged use at high doses – gastralgia, nausea, vomiting.

Overdose:

Symptoms: nausea, vomiting, diarrhea, dyspepsia.

Treatment: artificial vomiting, gastric lavage in the first 1-2 hours after taking the drug; reception of fat-containing products.

Interaction with other drugs:

Joint application with antitussive drugs (eg, containing codeine) leads to difficulty sputum discharge on the background to reduce coughing.

Increases penetration in bronchial secretion of amoxicillin, cefuroxime, erythromycin and doxycycline.

Special instructions:

 

It should not be combined with antitussive drugs that prevent removal of phlegm.

Patients taking medication masteron side effects retard should not recommend performance of breathing exercises.

In critically ill patients should be performed aspiration of liquefied sputum.

Do not take the medication masteron side effects retard immediately before bedtime.

 

Product form:

Capsules of 75 mg of prolonged action.

 

At 10, 14, 15 or 20 capsules in blisters of PVC film and aluminum foil printed patent.

At 1, 2, 3 contour cell package, along with instructions for use are placed in a pile of cardboard. injectable testosterone for sale