Pharmacological action masteron propionate (the active metabolite of bromhexine) is a mucolytic drug that improves the rheological properties of sputum, reducing its viscosity and adhesive properties, which contributes to its removal from the airways.
masteron propionate stimulates the activity of serous cells of bronchial tubes glands, production of enzymes that break down the relationship between sputum polysaccharides , the formation of surfactant and directly activity of the cilia of the bronchi, preventing them from sticking together.
After oral administration, the therapeutic effect occurs within 30 minutes and lasts for 6-12 hours (depending on the dose).
Ambrobene – Solution for oral and inhalation is used for diseases of the respiratory tract with separation of viscous sputum and difficulty sputum discharge:
– acute and chronic bronchitis, pneumonia;
– Hypersensitivity to masteron propionate and / or other components of the formulation,
– gastric ulcer and duodenal ulcer;
– epileptic syndrome
By limiting the functional ability of the kidneys and / or severe liver disease Ambrobene should be taken with extreme caution, reducing the applied dose and increasing the time between doses of the drug (normally under these conditions treatment is carried out under the supervision of a physician).
With great caution and only under medical supervision Ambrobene should be applied in cases dysmotility bronchi and large amounts of allocated secret (the danger of stagnation secretion in the bronchi).
Use during pregnancy and lactation
Despite the fact that to date there is no reliable data about the negative effects of masteron propionate on the fetus and infants, use Ambrobene during pregnancy, especially in the I trimester and during lactation is possible only after a thorough analysis of benefit / risk ratio attending physician.
DOSAGE AND ADMINISTRATION The use of inside: Inside Ambrobene drug is taken after a meal with a sufficient quantity of liquid (eg, water, juice or tea) using the supplied measuring cup. The following dosage commonly used (1 mL of solution contains 7.5 mg of masteron propionate): Children up to 2 years taking 1 ml, 2 times a day (15 mg / day). Children aged 2 to 6 years taking 1 ml three times a day (22.5 mg / day). Children aged 6 to 12 years by taking 2 ml of solution 2-3 times a day (30-45 mg / day). Adults and adolescents in the first 2-3 days of treatment taking 4 ml 3 times per day (90 mg / day) during the following days 4 ml solution, 2 times a day (60 mg / day). inhalation: When applying Ambrobene by inhalation can be any equipment (excluding steam inhalation). Before inhalation, the drug is mixed with 0.9% sodium chloride solution (for optimal humidification can be diluted in the ratio 1: 1) and heated to body temperature. Inhalation should be performed in the usual mode of breathing (not to provoke cough shock). Patients suffering from bronchial asthma, in order to avoid non-specific respiratory irritation and spasm before the inhalation of masteron propionate should be used bronchodilators. Typically, use the following dosage (1 mL of solution contains 7.5 mg of masteron propionate): Children under 2 years old inhaled by 1 ml 1-2 times a day (7.5-15 mg / day). Children from 2 to 6 years 2 ml of solution 1-2 times a day (15-30 mg / day). children older than 6 years and adults inhaled by 2.3 ml 1-2 times a day (15-45 mg / day). children to Treatment 2 years carried out only under the supervision of a physician. in the recommended drinking plenty of fluids while taking Ambrobene drug. It is not recommended to use Ambrobene without a doctor’s appointment more than 4-5 days.
Occasionally can develop weakness, headache, dry mouth and airways, excessive salivation, rhinorrhea, gastralgia, nausea, vomiting, diarrhea, constipation, dysuria, rash. In very rare cases there may be allergic reactions (rash, angioedema person, respiratory failure, temperature reaction with chills). It has been reported that in some cases were observed allergic contact dermatitis, and in one case observed the occurrence of anaphylactic shock.
INTERACTION WITH OTHER DRUGS
Concomitant use with drugs having antitussive activity (eg, containing codeine) is not recommended because of difficulties removing phlegm from the bronchial tubes in the background to reduce coughing.
Co-administration with antibiotics (amoxicillin, cefuroxime, erythromycin, doxycycline) improves pulmonary delivery of antibiotics in the way. Such interaction with doxycycline widely used for therapeutic purposes.
masteron propionate is well tolerated when administered at a dose of 25 mg / kg per day. Symptoms: increasing saliva, nausea, vomiting, decreased blood pressure. Treatment: gastric lavage in the first 1-2 hours after taking the drug, taking fat-containing products; necessary to monitor the hemodynamics and holding, if necessary, symptomatic therapy.
dark glass bottles containing 40 ml or 100 ml of the product, with cork-dropper and screw cap. 1 bottle with enclosed measuring cup and information to consumers in a cardboard box. mexican steroids for sale uk steroid can you buy steroid nasal sprays over the counter