Included in the masteron 100 preparation AMINE masteron 100 6% of natural amino acids are physiological komponentami.Posle parenteral administration, they are included in the free amino acid pool of the body and participate in all metabolicheckih processes, in particular, are used for protein synthesis.The bioavailability of the drug amine masteron 100e 6% by intravenous administration is 100%. Amino acids are included in the total pool of free amino acids in the body and distributed interstitial fluid and extracellular space of tissues and organs. The concentration of free amino acids in the cytoplasm of cells and blood plasma is regulated within a narrow range depending on the masteron 100 age, nutritional status and general condition of the patient. With the proper introduction (slowly and with constant speed) amine masteron 100e 6% does not violate the balance of amino acids. In severe violations of liver and kidney function regulation of amino acid balance is disrupted. In these cases, you should use special prescription amino acid solutions for parenteral nutrition. Only a small part of the amino acid is eliminated by the kidneys. Amino period plasma half-life masteron cycle is heavily dependent on age.
Indications for use:
Amine masteron 100e 6% for partial parenteral nutrition in neonates, masteron 100s and premature. Together with solutions of carbohydrates, fat emulsions, as well as vitamin preparations, electrolytes and trace elements provide total parenteral nutrition.
As with other amino acid solutions of amine masteron 100e 6% should not be administered with amino acid metabolism disorders, and metabolic acidosis, overhydration, hypokalaemia. In hepatic and renal insufficiency requires an individual dosage.
Dosage and administration:
masteron 100 AMINE 6% for long intravenous drip, mainly in the central vein.
Maximum injection speed: 0.1 g of amino acids per 1 kg of body weight per hour = 1.67 ml / kg.
The maximum daily dose:
children under 1 year – amino 1.5-2.5 g per 1 kg of body weight, or from 25 ml to 40 ml of 6% aminic masteron 100e per 1 kg of body weight per day.
children 2-5 years – 1.5 g of amino acids per 1 kg of body weight or 25 ml per 1 kg of body weight per day.
masteron 100 AMINE 6% is applied as long as the need for parenteral nutrition.
In parenteral nutrition of young children should take into account the following indicators: nitrogen urine, ammonia, glucose, electrolytes, triglycerides (for additional administration of fat emulsions), liver enzymes, serum osmolarity, acid-base balance and water-salt metabolism.
Too rapid infusion could result in loss of amino acids through the kidneys, and thus, to the amino acid imbalance.
Solutions of amino acids due to the increased risk of microbial contamination should not be mixed with other drugs. Open vial amine ifant 6% should be stored in a refrigerator at a temperature no higher than 10 ° C for up to 24 hours.
Avoid add other drugs to the formulation AMINE masteron 100 6%, it may cause toxic reactions. In any case ensure compatibility agents, preserving sterility and thoroughly mixed. The solutions with the addition of other medications can not be stored.
When used properly, it is not revealed. When infusion of the drug amine masteron 100e 6% in peripheral veins may be observed signs of local reactions: redness, phlebitis, thrombosis. Recommended daily monitoring of the catheter insertion site.
If you exceed the dosage and rate of administration of the drug amine masteron 100e 6%, as an overdose of other amino acid solutions, there are chills, nausea, vomiting, kidney aminoatsidoz. Also may experience acute circulatory disorders. In this case, the introduction of the drug should be discontinued immediately. When hyperkalemia enter from 200 to 500 ml of 5% glucose solution with 3.1 IU insulin per 3.5 g of glucose.